Will Using CBD Make Me Test Positive On A Drug Test?

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Summary:

Many prospective CBD users are concerned about drug testing, including pre-employment drug-testing. While both CBD and THC comes from the same place, they are different substances and will react differently to drug tests. To test for marijuana use, a Cannabinoid Screen and Confirmation (Urine) may be used. Will CBD show up on a Cannabinoid Screen?

In this article, we discuss drug testing, pre-employment drug screening, marijuana-specific drug screening, what CBD is, CBD vs. THC, false positives with CBD, and 100% safe CBD products.

Will Using CBD Make Me Test Positive On A Drug Test?

Man Vaping, Credit: Stock Photography
Man Vaping

Many prospective CBD users are concerned about drug testing, including pre-employment drug-testing. They are concerned that prolonged use or heavy use of CBD products may test as a false positive on standard drug tests.

Drug Testing

What is drug testing?

A drug test looks for the presence of one or more illegal or prescription drugs in your urine, blood, saliva, hair, or sweat. Urine testing is the most common type of drug screening. The drugs most often tested for include:

  • Marijuana
  • Opioids, such as heroin, codeine, oxycodone, morphine, hydrocodone, and fentanyl
  • Amphetamines, including methamphetamine
  • Cocaine
  • Steroids
  • Barbiturates, such as phenobarbital and secobarbital
  • Phencyclidine (PCP)

Drug Testing

Pre-employment Drug Screening

One of the most common types of drug testing is the pre-employment drug screen.

As part of the application process, job applicants may be required to be screened for drug and alcohol use. Depending on state law and company policy, employers may do this prior to making a job offer or as a contingency for an offer. Employees may be tested for drugs or alcohol in the workplace, where permitted by state law.

There are a variety of employment-related drug and alcohol tests used by employers. The types of drug tests that show the presence of drugs or alcohol include urine drug tests, blood drug tests, hair drug tests, breath alcohol tests, saliva drug screens, and sweat drug screens.

Things You Should Know About Pre-Employment Drug Testing

Urine Sample, Credit: Stock Photography
Urine Sample

The “Marijuana” Drug Test

To test for marijuana use, a Cannabinoid Screen and Confirmation (Urine) may be used. This test is sometimes called a marijuana screen, drug abuse screening test, DAST, marijuana drug test (urine), or drug abuse test.

This is a two-part urine test to look for delta-9-tetrahydrocannabinol, or THC. THC is the active ingredient in marijuana. The test can find out if THC or related chemicals from marijuana called metabolites are in your urine. The test is considered quite accurate. You may have to do the urine test in a healthcare provider’s office or with a technician present.

Cannabinoid Screen and Confirmation (Urine)

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Medical Technician

What Is CBD?

What is CBD or cannabidiol?

CBD oil is botanical oil made from the stalks and seeds of cannabis plants that are naturally abundant in CBD and low in THC, such as hemp. A specialized extraction process is used to yield highly concentrated CBD oil that also contains highly nutritious elements, including omega-3 fatty acids, vitamins, minerals, terpenes, chlorophyll, and amino acids.

CBD hemp oil is different from hemp oil found in most grocery and health food markets, which are likely created using hemp seed oil and contain only trace amounts of CBD. While nutritious, hemp seed products contain extremely low levels of CBD per weight, making them inadequate for those seeking CBD’s balancing effects.

As the demand for CBD hemp oil has grown over recent years, the market has responded by developing new types of CBD hemp oil products. There are now dozens of different types of CBD hemp oil products on the market. Pure CBD oil, which can be taken on its own, is now available as capsules, drops, tinctures, liquids, and even chewing gum.

For patients who are interested in avoiding even trace levels of THC found in most CBD hemp oil products, zero-THC CBD hemp oil products have recently become available in most major markets.

Does CBD Oil Get You High?

Marijuana Leaf, Credit: Stock Photography
Marijuana Leaf

CBD Vs. THC

While both CBD and THC comes from the same place, they aren’t the same thing.

Despite their similar chemical structures, CBD and THC don’t have the same psychoactive effects. In fact, CBD is a nonpsychoactive compound. That means it doesn’t produce the “high” associated with THC.

THC binds with the cannabinoid 1 (CB1) receptors in the brain. It produces a high or sense of euphoria.

CBD binds very weakly, if at all, to CB1 receptors. In fact, it can interfere with the binding of THC and dampen the psychoactive effects.

CBD vs. THC: What’s the Difference?

False Positives With CBD

Fortunately, the urine drug screen for THC-COOH is known to have very little cross-reactivity to other cannabinoids that are not intoxicating, such as CBD (cannabidiol), CBG (cannabigerol), CBN (cannabinol), and others. This is good news for “normal” consumers of CBD/hemp oil.

That said, individuals using unusually large doses of a cannabinoid-rich hemp oil product (above 1000-2000 mg of hemp oil daily) could theoretically test positive during the initial urinary screen. Although very rare, the urine screen in these cases would likely represent a “false positive” due to other non-THC metabolites or compounds, which may cross-react with the immunoassay. When this is the case, the confirmatory GC/MS test would be negative, since CBD and other cannabinoids will not be detected by the more accurate (and specific) GC/MS screen.

Does Using CBD Hemp Oil Result in a Positive Drug Test for THC or Marijuana?

100% Safe CBD Products

To avoid any potential false positives with CBD products, we recommend using a CBD product with 0% THC content. Products like TheraJoy, which are made using CBD isolate, contain no THC. Without any THC, you can’t create the “false positive” condition, so you won’t fail a drug test.

At TheraJoy, we always use the finest quality ingredients in our line of CBD topical products. We use 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. TheraJoy offers purity you can trust, guaranteed. We are always organic, vegan, gluten-free, and kosher. To maximize the benefits of our products make them part of your daily regime.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

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Understanding CBD Drug Interactions

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Summary:

Whenever multiple drugs are taken, there is a chance an interaction among the drugs will occur. Virtually all chemical compounds, from over-the-counter drugs and prescription pharmaceuticals to illicit substances, interact with other compounds. Drug interactions are complex and often unpredictable. A known interaction may not occur in every individual. While CBD produces very few side-effects and is considered to be generally safe for use, there are some risks that should be properly understood by all CBD users.

In this article, we discuss drug interactions, predicting drug interactions, additive vs. synergistic interactions, CBD drug interactions, the cytochrome P450 enzyme system, documented CBD drug interactions, and the grapefruit test.

Understanding CBD Drug Interactions

Woman Holding Prescription Pill, Credit: Stock Photography
Woman Holding Prescription Pill

Whenever multiple drugs are taken, there is a chance an interaction among the drugs will occur. The chemical interactions may increase or decrease the effectiveness of the drugs or their side effects, and the chances of drug interactions increase with the number of drugs being taken.

Drug Interactions

Whenever you consume a chemical compound, you must consider the possible interactions. Even innocuous and common chemicals like caffeine have interactions, some of which can be severe. Similarly, cannabidiol, while well tolerated by most users, has some interactions.

Virtually all chemical compounds, from over-the-counter drugs and prescription pharmaceuticals to illicit substances, interact with other compounds. There are, for example, 82 identified drug interactions with caffeine (of which 25 are classified as moderately severe to severe). Even seemingly benign substances, like grapefruit, are known to interact with many prescription drugs.

How Does Cannabis Interact With Other Drugs?

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Senior and Adult Daughter

Can Drug Interactions Be Predicted?

Drug interactions are complex and often unpredictable. A known interaction may not occur in every individual. This can be explained because there are several factors that affect the likelihood that a known interaction will occur. These factors include differences among individuals in their:

  • genes,
  • physiology,
  • age,
  • lifestyle (diet, exercise),
  • hydration,
  • underlying diseases,
  • drug doses,
  • the duration of combined therapy, and
  • the relative time of administration of the two substances. (Sometimes, interactions can be avoided if two drugs are taken at different times.)

Drug Interactions

Additive Vs. Synergistic

Before discussing CBD drug interactions further, it’s important to understand interactions in terms of medicine and pharmacology. There are two types of interactions – additive and synergistic.

Additive simply means the interaction between two chemicals equals the sum of their parts (e.g. 1+1 = 2). Synergistic means that when two chemicals interact, the effect is greater than the sum of their parts (e.g. 1+1 = 3. Sounds like “alternative math!”).

How Does Cannabis Interact With Other Drugs?

CBD Drug Interactions

While CBD produces very few side-effects and is considered to be generally safe for use, there are some risks that should be properly understood by all CBD users.

Research has begun to demonstrate that cannabidiol (CBD) has the potential to effectively help a large number of people. CBD interacts with the endocannabinoid system in a way that produces very few unintended side-effects.

While the majority of the vast majority of the science indicates CBD is safe for use and consumption, it does pose a few risks that, if not properly understood, could be dangerous.

Drugs that May Interact with CBD Oil

Scientist With Notepad, Credit: Stock Photography
Scientist With Notepad

Cytochrome P450 Enzyme System

Part of your liver, the cytochrome P450 enzyme system is responsible for metabolizes any potentially toxic compounds you ingest, including over 60% percent of any drugs you have ever consumed.

CBD can inhibit the cytochrome P450 system’s ability to metabolize certain drugs, leading to an overall increase in processing times.

One of these risks is the inhibition of the cytochrome P450 enzyme system.

According to Davis’s Drug Guide, this system contains more than 50 enzymes that process and eliminate toxins.

Drugs that May Interact with CBD Oil

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Assortment of Pills

Documented CBD Drug Interactions

What drugs should you be concerned about? Due to the fact that the cytochrome P450 is well-documented, there is a list of known interactions.

Any drug metabolized by CYP450 enzymes could potentially interact with cannabidiol. According to the Indiana University Department of Medicine, drugs known to use the CYP450 system include:

  • Anesthetics
  • Angiotensin II Blockers
  • Anti-epileptics
  • Antiarrhythmics
  • Antibiotics
  • Antidepressants
  • Antihistamines
  • Antipsychotics
  • Benzodiazepines
  • Beta-blockers
  • Calcium Channel Blockers
  • HIV Antivirals
  • HMG CoA Reductase Inhibitors
  • Immune Modulators
  • NSAIDs
  • Oral Hypoglycemic Agents
  • PPIs
  • Prokinetics
  • Steroids
  • Sulfonylureas

This list does not include all of the potential medications impacted by cannabidiol. Nor will every medication in the categories contained on this list will cause an interaction. For these reasons, you should consult with a medical professional before supplementing with CBD.

Drugs that May Interact with CBD Oil

Another potential interaction could come in the form of prodrugs. A prodrug is compound that, on administration, must undergo chemical conversion by metabolic processes before becoming an active pharmacological agent; a precursor of a drug.

Grapefruit, Credit: Stock Photography
Grapefruit

The Grapefruit Test

If you are taking another medication not found on the list above, and are still concerned about a possible interaction with CBD, then we recommend the grapefruit test.

Have you ever been told not to take your medication with grapefruit? This is because compounds in grapefruits can interfere with the metabolism of many medications.

CBD does the same thing. But as I said above, the effect is even stronger with CBD.

Do the grapefruit test with your doctor or pharmacist. Ask them: “Should I avoid eating grapefruits or drinking grapefruit juice with this medication?”

They will know exactly what you are talking about. If they say yes, you should avoid grapefruits with your medication, you now know you need to be careful about mixing CBD with those same meds as well. Talk to your doctor about CBD and tell them about it if they say you should avoid grapefruits with your medication.

CBD and Drug Interactions: An Easy Guide

At TheraJoy, we are proudly a market leader in topical CBD products. TheraJoy is always made with 99% pure CBD derived from medical grade, non-GMO hemp, sourced directly from Switzerland. We offer purity you can trust, guaranteed.

Remember, always consult your doctor before you begin taking a supplement or make any changes to your existing medication and supplement routine. This blog post is not intended to be medical advice, but it is information you can use as a conversation-starter with your doctor at your next appointment.

🏝️Hope you all are having a wonderful weekend 😎⁠

💛TheraJoy
...

11 1

🏝️Try TheraJoy - Feel better!⁠
100% no-questions-asked satisfaction guarantee. TheraJoy is purity you can trust, guaranteed!⁠
...

17 1
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